Asian Journal of Pharmaceutical Research and Health Care

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Unusual Localised Skin Reaction due to Ondansetron: Case Series


Affiliations
1 Department of Pharmacology, Smt B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed University, Piparia – 391760, Gujarat, India
2 Department of Paediatric, GMERS Medical College, Gotri, Vadodara – 390021, Gujarat, India
3 Department of Pharmacology, Nootan Medical College and Research Centre, Sankalchand Patel University, Visnagar – 384315, Gujarat, India
4 Department of Physiology, Smt B.K Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed University, Piparia – 391760, Gujarat, India
 

Ondansetron is an antiemetic drug that belongs to 5-hydroxytryptamine (5-HT3) receptor antagonists group. It has been widely used to treat nausea and vomiting due to chemotherapy, post surgery or due to any other gastrointestinal problem with 5-HT3 receptors involvement. The typical adverse drug reactions of Ondansetron include headache, dizziness, constipation or diarrhoea. Here, we have observed the skin reaction around the site of injection following Ondansetron administration. Recognition of this hypersensitivity reaction may allow better preparedness of clinicians to manage this condition.


Keywords

Ondansetron, 5-HT3, Skin Reaction.
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  • Unusual Localised Skin Reaction due to Ondansetron: Case Series

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Authors

Shruti Brahmbhatt
Department of Pharmacology, Smt B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed University, Piparia – 391760, Gujarat, India
Vihang Brahmbhatt
Department of Paediatric, GMERS Medical College, Gotri, Vadodara – 390021, Gujarat, India
Nehal Shah
Department of Pharmacology, Nootan Medical College and Research Centre, Sankalchand Patel University, Visnagar – 384315, Gujarat, India
Mahavirsingh Rajput
Department of Physiology, Smt B.K Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed University, Piparia – 391760, Gujarat, India

Abstract


Ondansetron is an antiemetic drug that belongs to 5-hydroxytryptamine (5-HT3) receptor antagonists group. It has been widely used to treat nausea and vomiting due to chemotherapy, post surgery or due to any other gastrointestinal problem with 5-HT3 receptors involvement. The typical adverse drug reactions of Ondansetron include headache, dizziness, constipation or diarrhoea. Here, we have observed the skin reaction around the site of injection following Ondansetron administration. Recognition of this hypersensitivity reaction may allow better preparedness of clinicians to manage this condition.


Keywords


Ondansetron, 5-HT3, Skin Reaction.

References





DOI: https://doi.org/10.18311/ajprhc%2F2021%2F27967