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Lichen Planus Vs Lichenoid Reaction: A Comprehensive Review
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Lichen planus (OLP) is relatively common, chronic dermatologic disease that frequently affects oral mucosa besides skin, genital mucosa, scalp and nails. Oral lichenoid reaction (OLR) represent a prevalent endpoints for extrinsic agents (allergens, medicines, dental materials) modified self antigens or superantigens. In lichen planus, an immune mediated pathogenesis is acknowledged although the correct causative agent is unknown. Despite comparable clinicopathological characteristics: etiology, diagnosis and prognosis between OLP and OLR. Diagnosis of OLP is established either by clinical or by clinical and histopathologic confirmation. Histopathologic features of OLP and OLR are similar with suggestions of certain discriminatory features by some authors.The significant role played in the diagnostic process by the inclusion of the clinician and the oral pathologist. In this article, etiopathogenesis, diagnosis, management, malignant transformation of OLP and OLR is reviewed.
Keywords
Lichen planus, Lichenoid Reaction, Dermatologic Disease, Oral Pathologist.
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