Pharmacological Activities of Benzimidazole Derivatives - An Overview

Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic Significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. Benzimidazoles are remarkably effective compounds both with respect to their bacteria inhibitory activity and their favorable selectivity ratio. Extensive biochemical and pharmacological studies have confirmed that these molecules are effective against various strains of microorganisms. This comprehensive overview summarizes the chemistry of different derivatives of substituted benzimidazole along with their antimicrobial activity.