Asian Journal of Research in Chemistry

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New Substituted M-phenoxy Chalcones, their Synthesis by Microwave Irradiation and Antifungal Activity


Affiliations
1 Department of Chemistry, B.N.P.G. College, M.L.Sukhadia University, Udaipur-313001 (Raj.), India
     

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Chalcones represent a group of compounds with interesting biological activities that are formed from a Claisen- Schmidt condensation between a aromatic benzaldehyde and an acetophenones in the presence of sodium hydroxide NaOH as a catalyst. A m-phenoxy benzaldehyde reacted with substituted aromatic acetophenones in presence of base to formed chalcones. The structures of all the synthesized compounds have been confirmed by elemental analysis and spectral data. The synthesized compounds have been tested for their antifungal activity.

Keywords

Microwave, Chalcones, Antibacterial Activity
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  • New Substituted M-phenoxy Chalcones, their Synthesis by Microwave Irradiation and Antifungal Activity

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Authors

Laxmi Lal Dangi
Department of Chemistry, B.N.P.G. College, M.L.Sukhadia University, Udaipur-313001 (Raj.), India
Mangal S. Dulawat
Department of Chemistry, B.N.P.G. College, M.L.Sukhadia University, Udaipur-313001 (Raj.), India
Parul Tiwari
Department of Chemistry, B.N.P.G. College, M.L.Sukhadia University, Udaipur-313001 (Raj.), India
Shiv Singh Dulawat
Department of Chemistry, B.N.P.G. College, M.L.Sukhadia University, Udaipur-313001 (Raj.), India

Abstract


Chalcones represent a group of compounds with interesting biological activities that are formed from a Claisen- Schmidt condensation between a aromatic benzaldehyde and an acetophenones in the presence of sodium hydroxide NaOH as a catalyst. A m-phenoxy benzaldehyde reacted with substituted aromatic acetophenones in presence of base to formed chalcones. The structures of all the synthesized compounds have been confirmed by elemental analysis and spectral data. The synthesized compounds have been tested for their antifungal activity.

Keywords


Microwave, Chalcones, Antibacterial Activity

References