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Drug Delivery Systems Based on Polymeric Micelles


Affiliations
1 Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114., India
2 Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114, India
     

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Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and blood circulation, as well as binding specificity to certain highly stressed receptors on the surface of cancer cells. y. The incorporation of these agents into nanoparticles reduces the adverse effects of standard chemotherapy on healthy tissues. Such nanoparticles, considered to be drug-transporting vehicles, are versatile and include micelles, liposomes, dendrimers, nanocapsules, nanospheres and more. Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and circulation, as well as binding specifications to certain more receptors expressed on the surface of cancer cells. When these drug-induced nanoparticles reach the plant surface, an external stimulus, such as ultrasound, can be used to introduce local and temporary drug release.

Keywords

Cancer, Chemotherapy, Drug release, Polymeric micelles, Triggered release.
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  • Drug Delivery Systems Based on Polymeric Micelles

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Authors

Priyanka Khot
Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114., India
Kavita Nangare
Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114, India
Vaishali Payghan
Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114., India
Tejashree Kamble
Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114., India
Santosh Payghan
Department of Pharamceutics Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist- Kolhapur (MH) 416114., India

Abstract


Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and blood circulation, as well as binding specificity to certain highly stressed receptors on the surface of cancer cells. y. The incorporation of these agents into nanoparticles reduces the adverse effects of standard chemotherapy on healthy tissues. Such nanoparticles, considered to be drug-transporting vehicles, are versatile and include micelles, liposomes, dendrimers, nanocapsules, nanospheres and more. Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and circulation, as well as binding specifications to certain more receptors expressed on the surface of cancer cells. When these drug-induced nanoparticles reach the plant surface, an external stimulus, such as ultrasound, can be used to introduce local and temporary drug release.

Keywords


Cancer, Chemotherapy, Drug release, Polymeric micelles, Triggered release.

References