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Extranodal Histiocytic Sarcoma Rectum: A Case Report


Affiliations
1 Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
2 Department of Surgery, IGMC - Shimla, India
     

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Histiocytic sarcoma (HS) is an exceedingly rare but aggressive hematopoietic tumor, showing morphologic and immunophenotypic features of mature tissue histiocytes. Diagnosis of HS is based on histological and immunohistochemical evidence of histiocytic differentiation supported by an extensive immunophenotypic analysis that excludes other large cell malignancies in the differential diagnosis. Search of world literature revealed only three previous reports of extranodal histiocytic sarcoma (ENHS) involving rectum specifically. We report a case of ENHS of rectum in a 65 year old man presenting with hematochezia. Radiological findings were indicative of polypoidal soft tissue mass lesion in rectum. Histopathology and immunohistochemical studies of the resected specimen confirmed the uncommon diagnosis ENHS.

Keywords

Histiocytic Sarcoma, Extranodal Histiocytic Sarcoma, Magnetic Resonance Imaging.
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  • Extranodal Histiocytic Sarcoma Rectum: A Case Report

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Authors

Vishal Bodh
Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
Rajesh Sharma
Department of Surgery, IGMC - Shimla, India
Brij Sharma
Department of Surgery, IGMC - Shimla, India
Rajesh Kumar
Department of Surgery, IGMC - Shimla, India
Puneet Mahajan
Department of Surgery, IGMC - Shimla, India

Abstract


Histiocytic sarcoma (HS) is an exceedingly rare but aggressive hematopoietic tumor, showing morphologic and immunophenotypic features of mature tissue histiocytes. Diagnosis of HS is based on histological and immunohistochemical evidence of histiocytic differentiation supported by an extensive immunophenotypic analysis that excludes other large cell malignancies in the differential diagnosis. Search of world literature revealed only three previous reports of extranodal histiocytic sarcoma (ENHS) involving rectum specifically. We report a case of ENHS of rectum in a 65 year old man presenting with hematochezia. Radiological findings were indicative of polypoidal soft tissue mass lesion in rectum. Histopathology and immunohistochemical studies of the resected specimen confirmed the uncommon diagnosis ENHS.

Keywords


Histiocytic Sarcoma, Extranodal Histiocytic Sarcoma, Magnetic Resonance Imaging.

References