The Indian Practitioner

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Is Biological Age a Better Indicator than Chronological Age for Metabolic Health?


Affiliations
1 Assistant Director - Clinical and Metabolic Laboratory, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
2 Hon Director Integrative Nutrition and Ayurceuticals, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
3 Director, Division of Endocrine and Metabolic Disorders, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
4 Research Director, Medical Research Centre-Kasturba Health Society, Vile Parle, India
     

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Our earlier studies have shown more advanced biological age than chronological age in obese women ≥ 40 years of age and particularly with greater visceral obesity. Advancement of age was also seen in women with Polycystic Ovarian Syndrome. Both obesity and Polycystic Ovarian Syndrome patients are known to be associated with metabolic dysfunction with underlying insulin resistance. Since metabolic syndrome is highly prevalent in Indian population, there is a pressing need for in-depth studies about how advancement of biological age over chronological age impacts health and longevity. In this article, we limit the review to the definition, dimensions, markers and predictors of biological aging.

Keywords

Biological Age, Chronological Age, HOMA IR, Metabolic Syndrome, PCOS.
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  • Is Biological Age a Better Indicator than Chronological Age for Metabolic Health?

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Authors

Shubhada V. Agashe
Assistant Director - Clinical and Metabolic Laboratory, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
Shobha A. Udipi
Hon Director Integrative Nutrition and Ayurceuticals, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
Rama A. Vaidya
Director, Division of Endocrine and Metabolic Disorders, Medical Research Centre-Kasturba Health Society, Vile Parle, Mumbai, India
Ashok D. B. Vaidya
Research Director, Medical Research Centre-Kasturba Health Society, Vile Parle, India

Abstract


Our earlier studies have shown more advanced biological age than chronological age in obese women ≥ 40 years of age and particularly with greater visceral obesity. Advancement of age was also seen in women with Polycystic Ovarian Syndrome. Both obesity and Polycystic Ovarian Syndrome patients are known to be associated with metabolic dysfunction with underlying insulin resistance. Since metabolic syndrome is highly prevalent in Indian population, there is a pressing need for in-depth studies about how advancement of biological age over chronological age impacts health and longevity. In this article, we limit the review to the definition, dimensions, markers and predictors of biological aging.

Keywords


Biological Age, Chronological Age, HOMA IR, Metabolic Syndrome, PCOS.

References