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Toxic Effects of Acrolyc Denture Teeth Resin, Lucitone 119 on Animal Model: Rats Wistar


Affiliations
1 Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, Algeria
2 Annaba University, Annaba, 23000, Algeria
3 N.& L. S. Department, Tebessa University, Tebessa, 12000, Algeria
     

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This study examines the potential toxic effects of lead compounds of an acrylic resin used in the manufacture of dental bases: the LUCITONE 119. The resin treatment is swallowed by diluting the compound in the drinking water of female Wistar rats. After treatment for 07 days and 21 days, average weights of animals and two organs (liver and spleen) are determined. Meanwhile, cellular blood components (red cells, hemoglobin, hematocrit, platelets, lymphocytes, monocytes and granulocytes) and haematological parameters (MCV, MCH and MCHC) were measured. The results show a disturbance in average weight of rats associated with that of the two organs involved (liver and spleen). Biochemical assays show a significant hematotoxicity mainly on platelets, hematocrit and leukocyte lineage.

Keywords

Acrylic Resin, Lucitone119, Wistar Rats, Hematological Toxicity, Blood.
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  • Toxic Effects of Acrolyc Denture Teeth Resin, Lucitone 119 on Animal Model: Rats Wistar

Abstract Views: 411  |  PDF Views: 2

Authors

Bouaricha Houda
Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, Algeria
Grifi Fatiha
Annaba University, Annaba, 23000, Algeria
Berrebbah Houria
Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, Algeria
Tadjine Aicha
Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, Algeria
Rouabhi Rachid
N.& L. S. Department, Tebessa University, Tebessa, 12000, Algeria
Djebar Mohammed-Réda
Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, Algeria

Abstract


This study examines the potential toxic effects of lead compounds of an acrylic resin used in the manufacture of dental bases: the LUCITONE 119. The resin treatment is swallowed by diluting the compound in the drinking water of female Wistar rats. After treatment for 07 days and 21 days, average weights of animals and two organs (liver and spleen) are determined. Meanwhile, cellular blood components (red cells, hemoglobin, hematocrit, platelets, lymphocytes, monocytes and granulocytes) and haematological parameters (MCV, MCH and MCHC) were measured. The results show a disturbance in average weight of rats associated with that of the two organs involved (liver and spleen). Biochemical assays show a significant hematotoxicity mainly on platelets, hematocrit and leukocyte lineage.

Keywords


Acrylic Resin, Lucitone119, Wistar Rats, Hematological Toxicity, Blood.

References