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Cresol from Toluene Metabolites in Head Space of Urine and Blood from Glue Sniffing Activity Using Gas Chromatography - Mass Spectrophotometry


Affiliations
1 Chemistry Department, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, 81310, Johor, Malaysia
     

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Glue sniffing has been an addiction problem to countries all over the world since late nineteenth century. Back then, it is the adults who are mostly abusers but recently, the trend have shifted towards younger generations. More teenagers have been recorded to be glue sniffers. Most literatures indicated that it is the volatile solvent present in glue, the substance that gives the abusers 'high' or the intoxicating effects that they pursue. To study the metabolites of these substances, blood and urine samples from positive glue abusers obtained from local agencies were analyzed. The results showed that there were significant amount of para- cresol in the head space which is one of toluene's metabolites.

Keywords

Glue, Toluene, Gas Chromatography-Mass Spectroscopy Detector, Head Space
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  • Cresol from Toluene Metabolites in Head Space of Urine and Blood from Glue Sniffing Activity Using Gas Chromatography - Mass Spectrophotometry

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Authors

Abdul Rahim Yacob
Chemistry Department, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, 81310, Johor, Malaysia
Mohd. Raizul Zainalibdin
Chemistry Department, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, 81310, Johor, Malaysia
Nazirah Said
Chemistry Department, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, 81310, Johor, Malaysia

Abstract


Glue sniffing has been an addiction problem to countries all over the world since late nineteenth century. Back then, it is the adults who are mostly abusers but recently, the trend have shifted towards younger generations. More teenagers have been recorded to be glue sniffers. Most literatures indicated that it is the volatile solvent present in glue, the substance that gives the abusers 'high' or the intoxicating effects that they pursue. To study the metabolites of these substances, blood and urine samples from positive glue abusers obtained from local agencies were analyzed. The results showed that there were significant amount of para- cresol in the head space which is one of toluene's metabolites.

Keywords


Glue, Toluene, Gas Chromatography-Mass Spectroscopy Detector, Head Space

References