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Protective Effects of Omega3 on CCl4-Induced Oxidative Stress and Nephrotoxicity in Female Albino Rats
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In the present study, twenty one female albino rats were used and they were divided in to three groups. This was carried out and designed to study the effect of omega 3 poly unsaturated fatty acid on carbon tetrachloride (CCl4) induced oxidative stress and kidney damage in female albino rats. However, the antioxidant activity of omega-3 were determined by assessing biochemical parameters (serum creatinine, urea, uric acid, and malondialdehyde (MDA)). Carbon tetrachloride caused significant increase in serum creatinine, urea, uric acid, and MDA level while, omega 3 significantly prevented the increase of the serum levels of creatinine, urea, uric acid, and MDA.
Keywords
Omega-3-Fatty Acids, Carbon Tetrachloride, Free Radicals, Malondialdehyde.
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