Indian Journal of Public Health Research & Development

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Role of Free Radicals in Cellular Signaling: A Review


Affiliations
1 Professor, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, India
2 MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, India
3 Professor, Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (BIHER) Pallikaranai, India
4 Associate Professor, Department of Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, India
5 Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College and Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, India
     

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Reactive oxygen species (ROS) were once considered to be deleterious agents, contributing to a vast range of pathologies. Both their damaging and beneficial effects are initiated when they target distinct molecules and consequently begin functioning as part of complex signal-transduction pathways. The recognition of ROS as signaling mediators has driven a wealth of research into their roles in both normal and pathophysiological states. The present review assesses the outline of current perspectives on redox-signaling mechanisms.

Keywords

Reactive Oxygen Species, Oxidative Stress, Nitric Oxide.
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  • Role of Free Radicals in Cellular Signaling: A Review

Abstract Views: 254  |  PDF Views: 0

Authors

Jayamathi Govindaraj
Professor, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, India
Keerthidaa Govindaraj
MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, India
S. Raghavendra Jayesh
Professor, Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (BIHER) Pallikaranai, India
Padmavathy Kesavaram
Associate Professor, Department of Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, India
U. Vidyarekha
Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College and Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, India

Abstract


Reactive oxygen species (ROS) were once considered to be deleterious agents, contributing to a vast range of pathologies. Both their damaging and beneficial effects are initiated when they target distinct molecules and consequently begin functioning as part of complex signal-transduction pathways. The recognition of ROS as signaling mediators has driven a wealth of research into their roles in both normal and pathophysiological states. The present review assesses the outline of current perspectives on redox-signaling mechanisms.

Keywords


Reactive Oxygen Species, Oxidative Stress, Nitric Oxide.