





Role of Prophylactic Antibiotics in the Surgical Treatment of Maxillofacial Fractures
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Objective: A systematic review of the literature was undertaken examining data to find the evidence of prophylactic administration of antibiotics inrelation to treating patients of maxillofacial fractures.
Study Design: Studies that fulfilled most of the requirements pertaining to it were retrieved. A computerized search was carried out using PubMed, and MEDLINE databases with the logical operators: "antibiotic" and "prophylaxis" and "maxillofacial trauma."
Results: A survey of these studies showed a drastic decrease in the infection rate of mandibular fractures in the antibiotic treated groups when being compared with the control groups. A variety of antibiotics had been used with an apparently constant effect. An "once a day" regimen ora 1-day treatment course had a similar or perhaps even better result than 7 days of treatment. No infections were corresponding to condylar, maxillary, or zygomafractures.
Conclusion: An "once a day" regimenor 1-day administration of prophylactic antibiotics seem to be the best documented to reduce infections.
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