Open Access
Subscription Access
Open Access
Subscription Access
Oral Mucoadhesive Drug Administration-A Short Review
Subscribe/Renew Journal
On focus with route of drug administration, the oral cavity is an attractive and the safest site for the delivery of drugs. As an advantage it can overcome acidic environment thereby causing instability of the drug, extensive first pass metabolism and low bioavailability of drug results an inadequate absorption. The buccal mucosa is rich in blood supply and relatively permeable. Buccal cavity was found to be most accessible site for both local and systemic delivery of drug. This review presents a brief description of advantages and limitations of oral mucosal drug delivery, mechanisms of drug permeation followed by current developments in this drug delivery systems.
Keywords
Drug, Buccal, Sublingual.
Subscription
Login to verify subscription
User
Font Size
Information
Abstract Views: 147
PDF Views: 0