Research Journal of Pharmacy and Technology

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A Review on Transbuccal Drug Delivery System and its Commercially Available Products


Affiliations
1 Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
     

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Buccal route is one of the promising area where continuous research is going on in order to increase the bioavailability of most of the drugs effected by first pass metabolism and also to increase possibility of oral delivery of protein and peptide drugs with high patient compliance. In order to achieve the required target of bioavailability, drugs are formulated in different buccal dosage forms. The objective of this article is to enlighten the commercial products of various buccal dosage forms and their evaluation.

Keywords

Buccal Route, First Pass Metabolism, Bioavailability, Oral Mucosa, Marketed Products
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  • A Review on Transbuccal Drug Delivery System and its Commercially Available Products

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Authors

M. Sunitha Reddy
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
Surekha
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
G. Anusha
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
S. Mallikarjun Reddy
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
K. Manasa
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India
G. Sowmya
Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India

Abstract


Buccal route is one of the promising area where continuous research is going on in order to increase the bioavailability of most of the drugs effected by first pass metabolism and also to increase possibility of oral delivery of protein and peptide drugs with high patient compliance. In order to achieve the required target of bioavailability, drugs are formulated in different buccal dosage forms. The objective of this article is to enlighten the commercial products of various buccal dosage forms and their evaluation.

Keywords


Buccal Route, First Pass Metabolism, Bioavailability, Oral Mucosa, Marketed Products

References